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Research Projects
Investigating the Functional Consequences of Novel EPHA2 Polymorphisms on KSHV Infectivity and KS Development Among South African HIV/AIDS Patients
Project ended 31 March 2022 Dr Georgia Schäfer Division of Medical Biochemistry, University of Cape Town Email Title of the project Investigating the functional consequences of novel EPHA2 polymorphisms on KSHV infectivity and KS development among South African HIV/AIDS patients. Project Description Kaposi’s Sarcoma (KS) is the most common Acquired Immune Deficiency Syndrome (AIDS)-related malignancy globally and […]
Read morePublished: 17 September 2018
Updated: 13 October 2025
Categories: Research Projects
Overcoming Glioma Resistance Through Lethal Autophagic Flux Control – A Multidisciplinary Approach
Project ended 30 June 2021 Prof Ben Loos Department of Physiological Sciences, Stellenbosch University Email Project Title Overcoming glioma resistance through lethal autophagic flux control – a multidisciplinary approach. Project Description The 2016 Nobel prize for medicine/physiology was awarded for the discovery of the cellular protein degradation and quality control process termed autophagy. Although we […]
Read morePublished: 17 September 2018
Updated: 8 April 2022
Categories: Research Projects
Verification of the Therapeutic Potential of LRP/LR Downregulation and anti-LRP/LR Antibody IgG1-iS18 for the Prevention of Tumour Formation and Metastasis in BALB/c Nude Mice
The project ended on 30 June 2021 The late Prof Stefan Weiss School of Molecular and Cell Biology, University of the Witwatersrand Email Title of the project Verification of the therapeutic potential of LRP/LR downregulation and anti-LRP/LR antibody IgG1-iS18 for the prevention of tumour formation and metastasis in BALB/c nude mice. Project Description Cancer plays a […]
Read morePublished: 13 September 2018
Updated: 7 February 2024
Categories: Research Projects
Impact of Cisplatin-induced Hearing Loss on Health-related Quality of Life: A Prospective Cohort Study
Project ended 30 June 2022 A/Prof Lebogang Ramma Department of Health & Rehabilitation Sciences, University of Cape Town Email Title of the project Impact of cisplatin-induced hearing loss on health-related quality of life: A prospective cohort study. Project Description Cisplatin is a highly effective and widely used chemotherapeutic drug for the treatment of solid tumours. […]
Read morePublished: 13 September 2018
Updated: 13 October 2025
Categories: Research Projects
Identification of Immunological Biomarkers Predictive of Pathological Response in Triple Negative Breast Cancer Patients Undergoing Neo-adjuvant Chemotherapy
Project ended 30 June 2020 Prof Bernardo Rapoport Department of Immunology, Faculty of Health Sciences, University of Pretoria Email Title of the project Identification of immunological biomarkers predictive of pathological response in triple-negative breast cancer patients undergoing neo-adjuvant chemotherapy. Project Description Although the incidence of breast cancer, which was reported to account for 1.7 million […]
Read morePublished: 12 September 2018
Updated: 11 February 2021
Categories: Research Projects
Responding to South Africa’s Childhood Cancer Challenges
Project ended 30 June 2021 Prof Alan Davidson Department of Paediatrics and Child Health, University of Cape Town; Western Cape Government Department of Health; Red Cross War Memorial Children’s Hospital Email Title of the project Responding to South Africa’s childhood cancer challenges: An in depth description of the epidemiology of paediatric cancer in the RCCH/GSH/UCT complex. This project […]
Read morePublished: 10 September 2018
Updated: 8 April 2022
Categories: Research Projects
Breast Cancer Progression Associated with Hypercoagulation and Chronic Inflammation
Project ended 30 June 2021 Dr Janette Bester Faculty of Health Sciences, Department of Physiology, University of Pretoria Email Title of the project Breast Cancer progression associated with hypercoagulation and chronic inflammation. Project Description To date, cancer remains one of the leading causes of death around the world. Of interest in this study is breast […]
Read morePublished: 10 September 2018
Updated: 8 April 2022
Categories: Research Projects
Type A projects which ended on 31 March 2017
The following Type A projects came to an end on 31 March 2017: Prof Riana Bornman – University of Pretoria. Biologically relevant genetic markers of prostate cancer risk and aggressive disease within South African men Dr Adrienne Edkins – Rhodes University. Analysis of stem-cell associated genes in breast cancer as biomarkers and predictors of cancer […]
Read morePublished: 11 December 2017
Updated: 11 December 2017
Categories: Research Findings, Research Projects
Modelling Impact of Prevention Strategies on Cervical Cancer Incidence in SA
Project ended 30 June 2020 Prof Alex Welte The DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis (SACEMA), University of Stellenbosch Email Title of the project Modelling the impact of prevention strategies on cervical cancer incidence in South Africa. Project Description In recent years, mathematical models are increasingly applied to cervical cancer research. Globally, […]
Read morePublished: 29 March 2017
Updated: 11 February 2021
Categories: Research Projects
Development of a Long Term Surveillance Programme Linked to an Integrated Rehabilitation Pathway for Upper Limb Morbidity in Breast Cancer Survivors in SA
Project ended 30 June 2021 Dr Delva Shamley Clinical Research Centre, Groote Schuur Hospital/ University of Cape Town Email Title of the project Development of a long term surveillance programme linked to an integrated rehabilitation pathway for upper limb morbidity in breast cancer survivors in South Africa. Project Description Lymphoedema and shoulder morbidity are well-documented […]
Read morePublished: 29 March 2017
Updated: 8 April 2022
Categories: Research Projects
TBX3 in Combination with c-Myc and Nucleolin as Multiple Markers for the Early Detection of Sarcomas
Project ended 30 June 2020 Prof Sharon Prince Department of Human Biology/Division of Cell Biology, University of Cape Town Email Title of the project TBX3 in combination with c-Myc and Nucleolin as multiple markers for the early detection of sarcomas. Project Description Sarcomas are highly diverse mesenchymal malignancies of the bone (osteosarcoma), blood vessels (angiosarcoma), […]
Read morePublished: 29 March 2017
Updated: 11 February 2021
Categories: Research Projects
Breast and Cervical Cancer Symptom Awareness in South Africa
Project ended 30 June 2020 Prof Jennifer Moodley Cancer Research Initiative, Faculty of Health Sciences, University of Cape Town Email Title of the project Breast and cervical cancer symptom awareness in South Africa. Project Description Breast and cervical cancer are the leading causes of cancer morbidity and mortality among women in South Africa (SA), with […]
Read morePublished: 29 March 2017
Updated: 19 July 2022
Categories: Research Projects
Surveillance of HPV genotypes among women with high-grade cervical cancer lesions attending Hospital Facilities in the former Transkei region of the Eastern Cape Province
Project ended 30 June 2021 Dr Zizipho Mbulawa Department of Pathology, Division of Medical Virology, University of Cape Town Email Title of the project Surveillance of HPV genotypes among women with high-grade cervical cancer lesions attending Hospital Facilities in the former Transkei region of the Eastern Cape Province. Project Description Specific types of human papillomavirus […]
Read morePublished: 29 March 2017
Updated: 8 April 2022
Categories: Research Projects
Breast/Ovarian Cancer Susceptibility in SA Women: Clinical Utility of Multi-gene Panel Testing
Project ended 30 June 2020 Prof Lizette Jansen van Rensburg Department of Genetics, University of Pretoria and Steve Biko Academic Hospital Email Title of the project Breast/ovarian cancer susceptibility in South African women: Clinical utility of multi-gene panel testing. Project Description Worldwide breast cancer is the most common cancer in women. In South Africa, breast […]
Read morePublished: 29 March 2017
Updated: 11 February 2021
Categories: Research Projects
Contraceptive Needs Fertility Intentions of Women with Breast Cancer in Cape Town
Project ended 30 June 2020 A/Prof Jane Harries Women’s Health Research Unit, School of Public Health and Family Medicine, Health Sciences Faculty, University of Cape Town Email Title of the project Contraceptive needs and fertility intentions of women with breast cancer in Cape Town: a qualitative exploratory study. Project Description Breast cancer remains the commonest […]
Read morePublished: 29 March 2017
Updated: 11 February 2021
Categories: Research Projects
Prostate Cancer Risk in South African Men
Project ended 30 June 2020 Prof Riana Bornman School of Health Systems and Public Health, University of Pretoria Email Title of the project Prostate cancer risk in South African men. Project Description Prostate cancer globally has one of the highest ethnic-based associations for any human cancer and population-based studies showed that African-Americans are 1.7 times […]
Read morePublished: 29 March 2017
Updated: 11 February 2021
Categories: Research Projects
Evaluation of Tumor Associated Antigens to Optically Label Cutaneous Basal Cell Carcinoma for Surgical Excision
Project ended 30 June 2021 Prof Stefan Barth Institute for Infectious Disease and Molecular Medicine, University of Cape Town Email Title of the project Evaluation of tumour-associated antigens to optically label cutaneous basal cell carcinoma for surgical excision. Project Description Basal cell carcinoma is the most common skin cancer worldwide with the second-highest incidence rates […]
Read morePublished: 29 March 2017
Updated: 8 April 2022
Categories: Research Projects
Major Finding: Rooibos protects against adverse effects of UVB exposure
From a soothing beverage to beauty elixir, Rooibos tea is one versatile brew. Now researchers have discovered that it can also undo some of the damage caused by the sun’s harmful rays. CANSA is proud to say that we have been involved in partly funding the research. Read about the CANSA Type A project: Chemopreventive potential of Rooibos in skin carcinogenesis
Read morePublished: 7 December 2016
Updated: 9 March 2021
Categories: Research Findings, Research Projects, SunSmart
Hodgkin Lymphoma in SA Children Adolescents
Project ended 31 March 2019 Dr Jennifer Geel Charlotte Maxeke Johannesburg Academic Hospital / WITS / South African Children’s Cancer Study Group Email Title of the project Hodgkin Lymphoma in South African Children Adolescents from 2000-2010: A first report by the South African Children’s Cancer Study Group. Project Description The purpose of this research is to see […]
Read morePublished: 5 April 2016
Updated: 8 April 2022
Categories: Research Projects
Type A Research Projects Per Researcher
B Barth, Stefan Prof (project ended 30 June 2021) Bester, Janette Dr (project ended 30 June 2021) Blackburn, Jonathan Prof (project ending 31 March 2027) Bornman, Riana Prof (project ended 30 June 2020) C Candy, Geoffrey Prof (project ended 30 June 2022) D Davidson, Alan Prof (project ended 30 June 2021) E Engelbrecht, Anna-Mart Prof (project ended […]
Read morePublished: 26 May 2012
Updated: 31 March 2026
Categories: Research Projects
CANSA Research Fundraising Project
Research Driving Health Education & Advocacy Donate here… CANSA ensures that the scientific findings and knowledge gained from our research, realign our advocacy focus (our watchdog role), to strengthen our health and care & support programmes, to the greater benefit of the public. The most cost effective long-term strategy for cancer control, is to help […]
Read morePublished: 26 May 2012
Updated: 30 September 2015
Categories: Research Projects
